19^th Nano Congress for Next Generation August 30-31, 2017 Brussels,Belgium

Biography:

Ying-Chieh Lee has completed his PhD at the age of 14 years from Departmant of Materials and Science and Engineering, National Chung-Hsin University. He is Dean of Office Research and Development, National PingTung University of Science and Technology. He has published more than 60 papers in reputed journals.

Abstract:

Ni-Cr-Mn-Y-Dy resistive thin films were prepared on glass and Al₂O₃ substrates by DC magnetron co-sputtering from targets of Ni-Cr-Mn-Y casting alloy and Dy metals. Electrical properties and microstructures of Ni-Cr-Mn-Y-Dy films under different proportion of elements and annealing temperatures were investigated. The phase evolution, microstructural and composition of Ni-Cr-Mn-Y-Dy resistive films were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM),  transmission electron microscopy (TEM) and Auger Electron Spectroscopy (AES). When the annealing temperature was set to 350 °C, the Ni-Cr-Mn-Y-Dy films with an amorphous structure was observed. It is found that the resistivity of Ni-Cr-Mn-Y films was increased with increasing of Dy content. The Ni-Cr-Mn-Y films with 33.2% Dy addition annealed at 300 °C which was exhibited the resistivity 1600 mW-cm with -8.2 ppm/°C of temperature coefficient of resistance (TCR).

Biography:

Seifelislam has completed his M.Sc. in sustainable energy from Hamad Bin Khalifa University and B.Sc. in mechanical engineering from Qatar University. He was awarded the first place award in the national scientific research forum in 2012. He has been working as a research assistant at the mechanical engineering department of Qatar University since 2013. His main research focus is heat transfer, thermofluids and dynamics, and nanotechnology. He has published several papers in reputed journals related to heat transfer and thermal comfort.

Abstract:

during hot summer months. By replacing the conventional single pipe evaporator with a double pipe evaporator in Heating Ventilating and Air Conditioning (HVAC) systems, there is a great potential for an enhanced thermal performance. In this study, a homogeneous nanofluid of dispersed Carbon Nano Tubes (CNT) was used as the secondary fluid in the double pipe evaporator of a 17 kW HVAC system. Three concentrations of CNT nanofluid of 0.025, 0.05, and 0.1 by weight percentage were circulated separately using a small 104 W pump connected to a 150 liters tank. The AC unit was placed in a 45 m³ balanced calorimeter of 2.24 kW heat load. Experimental results showed a promising reduction in the compressor work and an increase in the system Coefficient of Performance (COP). The collected data showed that system thermal performance depended on the evaporator secondary fluid flowrate more than condenser secondary fluid flowrate. By increasing the concentration of CNT nanofluid, the compressor work was shown to decrease while the COP was shown to increase. In comparison with the standard rated AC unit, utilizing a double-pipe evaporator and a condenser with maximum nanofluid concentration resulted in a decrease of about 52% in the compressor work and a similar percentage of increase in the system COP. As a result of the enhanced heat transfer, the operating electrical current was reduced by 30% in comparison to the rated compressor current.

Biography:

Claire Deeb has completed her Ph.D. from the University of Technology of Troyes (France) and postdoctoral research activities from Argonne National Laboratory (IL, USA) and Northwestern University (IL, USA). She currently is a research scientist at C2N - CNRS where she conducts research in the field of optics, active plasmonics, and nanophotonics. Claire is collaborating with leading groups at UIUC (IL, USA) and LMU-Munich and has led many international projects. She has given 11 invited talks and has published over 13 papers and one book chapter. Additionally, she has received 2 PhD awards and has been serving as an editorial board member of PNN.

Abstract:

Gaps formed between metal surfaces control the coupling of localized plasmons, thus
allowing gap-tuning targeted to exploit the enhanced optical fields for different applications. Classical electrodynamics fails to describe this coupling across sub-nm gaps, where quantum effects become important owing to non-local screening and spill-out of electrons.1-3 The advantages of narrow gap antennas have mostly been demonstrated for processes like SERS that are excited optically, but promising new phenomena appear when such antennas are fed by electric generators.1,4 However, the extreme difficulty of engineering and probing an electrically driven optical nanogap antenna has limited experimental investigations of physical concepts at stake in these conditions. The feasibility of structuring electron-fed antennas as nano-light sources has been recently demonstrated;4 however, this configuration remains very limited: too much power was lost as heat when operating the optical antenna, and the antenna operation time was limited by the structure lifetime to sustain a bias voltage for a few hours. The innovative structure that we suggest here will cope with all these limitations: ALD dielectric materials substitute the air gap to improve the antenna stability; a quantum efficiency of 10-1 is targeted owing to a significantly efficient antenna (2 orders of magnitude higher field enhancement). The resulting source will
operate at room temperature and have a tunable spectral response (ranging from visible frequencies to THz regime) defined by the antenna geometry and the applied bias.5 Also, this source will be compact, Si-compatible, and will not request specific emitting materials (e.g. III-V semi-conductors) to operate.

Biography:

I am fereidoon bondarian, PhD student, and I am working in two field, the first one is Nano material a defect of that on secondary metabolite and second one working on some Nano particles that made from some plant extracts like eucalyptus.

Abstract:

Increasing tendency of human societies to use medicinal plants and products derived from them, reducing the cultivation of medicinal plants, faced with extinction, the negative effects of some chemical drugs in the long time, the cost and time of extraction of secondary metabolites are reason of using modern methods to achieve faster and cheaper to this class of compounds. In view of the importance of Papaver somniferum and the only human resources to achieve significant analgesic alkaloids like Morphine, Codeine and Papaverine, this study aimed at evaluating the changes of two secondary metabolites of this plant Thebaine and Papaverine affects Nano elicitors copper oxide and zinc oxide on callus root in the cell suspension at two concentrations and three times. After reviewing the HPLC chromatogram of the sample and the rate of change tables of Papaverine and Thebaine were observed in samples treated with nano elicitors, Thebaine and Papaverine treated with 0.237 gr/ml nano copper oxide at 96 h after induction towards zero time and the comparison with the control sample at the same time is considerably reduced. Other results include the highest percentage Thebaine treated with 0.162 g/ml nano zinc oxide at 144 h after induction noted 94.6472%.

Biography:

Iman Farahbakhsh is currently an assistant professor of material science and metallurgy engineering at the Islamic Azad University in Iran. He has a BSC in material science and metallurgy engineering from Ferdowsi University of Mashhad and MSC in extractive metallurgy from Amirkabir University of Technology (Tehran Polytechnic) and PhD in Nanomaterials from Iran University of Science and Technology (IUST) and he was as visiting professor in Kumamoto University in Japan. He was involved in some international project till now and he has more than 10 ISI paper (WOS) in high quality journals and more than 40 international conference.

Abstract:

In this study, Fe50Ni50 alloy powders were synthesized by Mechanical alloying process using planetary high- energy ball mill (Pulverisette 5, Fritsch) for milling times: 2, 5, 10, 30, 50, 70 h and for the weight ratio of balls to powder (BPR) 30:1, under argon atmosphere. The alloy formation and different physical properties were studied as a function of milling time, using X-ray diffraction (XRD) technique, Field emission scanning electron microscopy (FESEM), Transmission Electron Microscopy (TEM), vibration sample magnetometer (VSM) and Fourier transform infrared (FTIR) spectroscopy. Increase in milling time, led to reduction in crystallite size (D) in the super paramagnetic phase, thus inducing a higher magnetization to the about 120 emu/g, which is significantly higher compared with the work of others. Also reduction in crystallite size led to lower coercivity. Optical studies showed that determined grain size based on hysteresis curve for 70h of milling time is in the same order of radiation wavelength.

Biography:

Prof. L. Q. “Rick” Wang received his PhD from University of Alberta (Canada) and is currently a full professor in the Department of Mechanical Engineering, the University of Hong Kong. He is also the Qianren Scholar (Zhejiang) and serves as the director and the chief scientist for the Laboratory for Nanofluids and Thermal Engineering, Zhejiang Institute of Research and Innovation (HKU-ZIRI), the University of Hong Kong. He has over 30 years of university experience in thermal & power engineering, energy & environment, transport phenomena, materials, nanotechnology, biotechnology, and applied mathematics in Canada, China/Hong Kong, Singapore and the USA, and 2 years of industrial experience in thermal engineering and technology management. Prof. Wang has secured over 70 projects funded by diverse funding agencies and industries including the Research Grants Council of Hong Kong, the National Science Foundation of China and the Ministry of Science and Technology of China, totaling > US$15m (excluding US$ 2.2 billion for AMS project). Prof. Wang has published 10 books/monographs and 356 book chapters and technical articles, many of which have been widely used by researchers all over the world, and is ranked amongst the top 1% of most-cited scientists (ESI). He has also filed 22 patent applications and led an international team in developing a state-of-the-art thermal control system for the Alpha Magnetic Spectrometer (AMS) on the International Space Station. The AMS project is headed by Professor Samuel C. C. Ting (Nobel laureate in Physics, MIT, USA) and is to search for antimatter, dark matter and spectra of cosmic rays.

Abstract:

Droplets of nanoliter and subnanoliter are useful in a wide range of applications, particularly when their size is uniform and controllable. Examples include biochemistry, biomedical engineering, food industry, pharmaceuticals, and material sciences. One example of their many fundamental medical applications is the therapeutic delivery system for delivering site-specific therapy to targeted organs in the body and as the carriers for newer therapeutic options. The size, the size distribution, the generation rate and the effective manipulation of droplets at a scale of nano, pico, femto and even atto liters are critical in all these applications.  We make an overview of microfluidic droplet generation of either passive or active means and report a glass capillary microfluidic system for synthesizing precisely controlled monodisperse multiple emulsions and their applications in engineering materials, nanofluids, microfibers, embolic particles and colloidosome systems. Our review of passive approaches focuses on the characteristics and mechanisms of breakup modes of droplet generation occurring in microfluidic cross-flow, co-flow, flow-focusing, and step emulsification configurations. The review of active approaches covers the state-of-the-art techniques employing either external forces from electrical, magnetic and centrifugal fields or methods of modifying intrinsic properties of flows or fluids such as velocity, viscosity, interfacial tension, channel wettability, and fluid density, with a focus on their implementations and actuation mechanisms. Also included is the contrast among different approaches of either passive or active nature.

Biography:

Zeeshan Ahmad is a Professor of Pharmaceutics & Drug Delivery at De Montfort University (The Leicester School of Pharmacy). He is a Royal Society Industry Fellow (working closely with BlueFrog Design) and also leads the EPSRC EHDA Network (a highly interdisciplinary initiative involving industry and academia). He obtained his first and Doctoral degrees from Queen Mary (University of London). He has broad research interests in medical materials, their engineering and ultimate applications for healthcare (interfacing at chemistry, biology, physics and biomedical engineering). Specifically, these include various modes of drug dosage form manufacturing (smart nanoparticles and microparticles, bubbles, fibrous materials, printed constructs and transdermal/skin contact systems), tissue engineering (scaffolds and cell guidance), medical device coatings (orthopaedic implants) and biomedical material synthesis (polymers and bioceramics). He also has a very keen interest in novel fabrication routes (EHDA, microfluidic and emulsion methods) to address healthcare challenges. He has published extensively in the field and his research has been supported by The Royal Society, EU, Leverhulme Trust, EPSRC and numerous industrial partners (from large Pharma to SME’s).

Abstract:

This talk will focus on the emergence, rapid growth and future development of electrohydrodynamic technologies (EHDA). These technologies arise from the impact of electrical stresses on liquid media flow and the talk will show how initial simple experiments have been transformed to yield very complex nano and micro structures as biomedical materials and biomaterials, covering aspects of drug delivery and biomedical engineering devices. The talk will demonstrate structure diversity and future potential for such technologies and details for current challenges will be shown. Furthermore, the talk will also discuss recent collaborative developments between industry and academia to take these ideas and concepts forward.

Biography:

Ola Mohamed get PhD in  Ain shamas university 2000, Associate Prof. in 2006 , Full Prof. in 2011.  Her fields of Interest; Leather technology,  Leather coating to improve its mechanical and physical properties. Using Nano technology in leather finishing, Recycling leather solid wastes and Recovery of chrome from tannery waste water using different nano- materials and techniques. Participate in many national and international conferences. PI for many international projects through scientific cooperation as France and China. Get and give many Training course and scientific Presentations.

Abstract:

Leather industry is one of the most pollutant industries in the world. It produces all types of environmental pollution especially in finishing step which uses organic hazards solvents. In order to minimize the environmental impact in leather industry, water-based recipes are proposed in leather finishing. The application of an acrylic emulsion as a top coat system provides an excellent balance of safety, performance and commerciality in comparison with other coats. Acrylic resin nanosize latex whose colloidal particle size is about 23 nm with solids content of about 25% was prepared by copolymerization of MMA and 2-EHA at different monomer ratios via micro emulsion polymerization technique. The best prepared copolymer so, it was modified with different ratios of silicon dioxide nanoparticles (1-5%), then studied the properties of the modified acrylic films and applied onto leather. The physical, chemical, mechanical and thermal properties of coated leather before and after silicon dioxide nanoparticles application were evaluated and discussed.

Biography:

Prof. Han-Yong Jeon, geosynthetics/technical organic materials researcher and he was the 32nd President of Korean Fiber Society (2014~2015). He has published more than 794 papers in domestic and international conferences. He wrote 19 texts including 'GEOSYNTHETICS’ and also published 117 papers in domestic & international journals. He has awards of Marquis Who'sWho - Science and Engineering in 2003~2016 and also, he got the 33rd Academy Award of Korean Fiber Society in 2006 and “Excellent Paper Award of 2012” by The Korean Federation of Science and Technology Societies.

Abstract:

“Green” revolution is rapidly increasing in every construction sites, especially between construction and societies’ needs. Furthermore, although durability of geosynthetics should be emphasized for long-term service period, durability controlled mechanism could be required to fulfil the short-term degradability purpose for green geosynthetics. “Green Geosynthetics” are made of eco-environmental biodegradable polymeric resins or natural materials and they must maintain their needed performance such as durability, design strength, hydraulic property etc. during service period in the application field. Then, after service period they should be degraded no harmful state in the soil structures. The important concept of green geosynthetics is focused on their degradable behaviours of used resins and needed performance for engineering qualification with technical data of designing. In this study, technical availability of green geosynthetics was introduced and reviewed to be related to the quantitative analysis of biodegradability of green geosynthetics by conceptual consideration through its evaluation. Still now, there is no international test method to evaluate the biodegradability of green geosynthetics performance and only the geosynthetics performance test methods of ISO and ASTM International are applied for this purpose. However, it is not reasonable for green geosynthetics to adopt these test methods directly and new test methods should be introduced for green geosynthetics performance testing. In this study, the regulation of evaluation method of biodegradability for green geosynthetics between index and field tests is proposed by connection key factor to confirm the biodegradable behaviors for green geosynthetics.

Biography:

Franco Palla, is an Associate professor of Environmental and Applied Botanical Sciences at the University of Palermo, Italy. He is the Coordinator of Five-Year Degree in Conservation and Restoration of Cultural Heritage Scientific at University of Palermo. He is the Coordinator of UNIPA Research Unit at Italian Technology for Advanced Applications in Cultural Assets. He is the head of the research Laboratory of Biology and Biotechnology for Cultural Heritage (LabBBCH) at the Department of Biological, Chemical, Pharmaceutical Sciences and Technology (STEBICEF) of University of Palermo. Currently Prof. Palla is Scientific Consultant for Biological deterioration, in restoration projects regarding archaeological sites, works of art, historic-artistic manifacts. He is author and co-author of more than 200 publications in national and international scientific journals and congress proceedings, Editor of the book Biology and Biotechnology for Cultural Heritage (Springer) and Coordinator of Scientific - Organizing Committee and Chair in National and International Conference.

Abstract:

In the last decade science and technology have provided protocols in defining innovative restoration strategies. In our laboratory bioactive molecules, isolated from plants or marine organisms, are characterized and applied in order to control the microbial colonization on historic-artistic manufacts. Similarly, these molecules are able to inhibit fungal and/or bacterial growth to acting like chemical biocides. Marine organisms also represent a source of cold-active enzymes (hydrolases) useful in biocleaning/bioremoval protocols, in order to remove protein or ester layers from the artwork surfaces.
These represent valid alternatives to conventional strategies, free from negative impacts on human health and environment.

Biography:

Krasikov E. is a Head of Laboratory, Department of Reactor Materials and Technologis at the National Research Centre ”Kurchatov Institute” (Moscow, Russia), with key qualification: responsible executor in Radiation Damage Physics of Solids. Master’s Degree in Material Science – 1970, Ph.D. – 1974, D.Sc. -2005. He has published more than 100 peer-reviewed papers.

Abstract:

Influence of neutron irradiation on reactor pressure vessel (RPV) steel degradation are examined with reference to the possible reasons of the substantial experimental data scatter and furthermore – nonstandard (non-monotonic) and oscillatory embrittlement behavior. In our glance this phenomenon may be explained by nanostructure evolution of steel during irradiation that result in self-organization appearance and presence of the wavelike recovering component in the embrittlement kinetics. We suppose that the main factor affecting steel anomalous embrittlement is fast neutron intensity (dose rate or flux), flux effect manifestation depends on state-of-the-art fluence level. At low fluencies radiation degradation has to exceed normative value, then approaches to normative meaning and finally became sub normative.

In our opinion controversy in the estimation on neutron flux on radiation degradation impact may be explained by presence of the wavelike component in the embrittlement kinetics. Therefore flux effect manifestation depends on fluence level. Owing to nanostructere evolution at low fluencies radiation degradation has to exceed normative value, then approaches to normative meaning and finally became sub normative. Paradoxically as a result of dose rate effect manifestation peripheral RPV’s zones in some range of fluencies have to be damaged to a large extent than situated closely to core.

We suppose that at some stages of irradiation damaged metal have to be partially restored by irradiation i.e. neutron bombardment. Nascent during irradiation nanostructure undergo occurring once or periodically evolution in a direction both degradation and recovery of the initial properties. According to our hypothesis at some stage(s) of metal nanostructure degradation neutron bombardment became recovering factor.

Biography:

Solleti Goutham obtained his M.Sc.(Nanoscience & Technology) Degree at the age of 23 from JNT University Hyderabad, India. Currently he is doing Ph.D. under the supervision of Dr.K.V.Rao from JNT University Hyderabad. His research topic is “Development of flexible Gas Sensor by novel nano materials”. His current area of research is chemiresistive gas sensors for detection of explosive and poisonous gases.

Abstract:

Hybrid nanomaterial (powdered fungi and ZnFe₂O₄) was developed and studied for gas sensing application, specifically for NO₂ gas detection. In this study, powdered Rhizopus species W3 and ZnFe₂O₄ nano-powder were mixed at equal proportion to carryout sensing experiments. The conjugated material film was coated on the interdigitated electrodes (IDEs) by drop drying method, to determine the NO₂ gas sensing characteristics. It was found that the response of these hybrid material decrease resistance, thereby resembling to p-type semiconductor. The fungi W3- ZnFe₂O₄ hybrid composite sensor showed better response, sensitivity, selectivity, stability and reproducibility at room temperature towards 30 ppm of NO₂. N. Miura et al reported in 2002 ZnFe₂O₄ shown good sensitivity for NO₂ (436 ppm) at 700 ÌŠC operating temperature [1]. Therefore, In the present work effort was made to prepare novel hybrid material that is feasible, eco-friendly, flexible, cost-effective, low maintenance and light weight new device.

Biography:

Zalak bhut has pursuing his bachalors degree in Nanotechnology at V.V.P. Engineering College of gujarat state. He complete his study withhigh rank, and worinkg on the cancer detection device. The device which are more functionable and very low cost. The reviwe article on “liver cancer” is on process.

Abstract:

In the present article overview of the implementation of nanotechnology in cancer treatment, using magnetic hyperthermia is presented. The revolution of human lifestyle has led to newdiseases. There are still many diseases in this world which can’t be diagnosed and have a cure for it. Cancer is one of them and stillit remains an unsolvedmystery. The survival percentage of cancer patients is 35%. But the revolution of latest technology promises to fight cancer. Due to harmful secondary effects of radiotherapy, magnetic hyperthermia proves to be an accurate solution for cancer.Chemotherapy is been used for over adecade and now it can be replaced by magnetic hyperthermia. Thus nanotechnology acts as an effective weapon in this new era to fight the cancer disease treatment.

Biography:

Jenan S.Kashan has completed hir PhD at 2014 from Unversity of Technology. She is the Scientific Assistant of Biomedical Engineering Department. She has published more than 15 papers in reputed journals and has been participated in The  UK Society for Biomaterials since 2013. (Up to 100 words)  
 

Abstract:

This paper presents the modified polymer matrix bio composite for bone analogue and replacement. The PP polymer employed as polymeric matrix to give robust properties, particularly when it uses with Nano ceramic filler. In this work, the Nano Calcium Carbonate (CaCO3) is proposed as a filer, and the optimum processing conditions for CaCO3/PP Nano composites represent the bone analogue biomaterials,  using the Enumerated data by MATLAB environment. The effects of the nano sized Al2O3 on the mechanical properties are also considered here. (ESM) using MATLAB program, provided an indication for optimum processing condition that prove the classical experiments design. The results show the optimum mechanical properties and uniform distribution of the fillers.

Biography:

Swati Patil has completed her PhD at the age of 27 years from Shivaji University, India. She is the PostDoctoral fellow at the School of Mechanical Engineerning, Chonnam National University, South Korea. She has published more than 20 papers in reputed journals with good impact factors. She have good background of electrochemistry and intrest on synthesis of nanomaterials. 

Abstract:

The electrode material with nanostructured features is a key point in electrochemical application to enhance the electrochemical activities. Nowadays, more researchers are concentrated on the synthesis of hierarchical nanostructured architecture with smaller particle size employing different synthesis tools. Without the use of an additive binder hydrothermal route was employed for the synthesis of self-assemble nanostructures of single (Ni₃S₂) and binary metal sulphides (NiCo₂S₄) with particle size near about 10 nm for assymmetric supercapacitor application. The prepared samples were used for structural and surface morphological studies using different characterization techniques and then electrochemical measurements were performed. Through the electrochemical measurements, a significant difference in the performances of both electrode materials was observed. Achieving the better electrochemical activities for CoNi₂S₄-µflower with 2098.95 F g^-1 specific capacitance, the asymmetric supercapacitor designed with Ni₃S₂-nanorod is one of the electrode. The designed hybrid asymmetric supercapacitor, based on Ni₃S₂-nanorod//CoNi₂S₄-µflower electrodes, exhibits a specific capacitance of 54.92 F g^-1 at a scan rate of 5 mV s-1. The assembled asymmetric supercapacitor has an energy density of 6.6 Wh kg^-1 while delivering a power density of 820 W kg^-1. The capacitive retention of the initial capacitance remains desirable at 89.13 % after 5000 CV cycles at a scan rate of 100 mV s^-1. The present work manifests a vision for the fabrication of self-assembled, binder-free electrodes for high-performance hybrid supercapacitor application.

Biography:

I have got bachelor’s degree and master degree from Metallurgy and Material Engineering at Yıldız Technical University, Ä°stanbul-TURKEY. During my undergraduate and graduate I have studied some projects about nanotechnology as ‘developing gas sensors’, ‘anti-viral and anti-microbial masks’ and ‘conservation historical documents’. Also I have made researches about archaeometallurgy and I have published a paper about this situtation in Journal of Turkish Studies-Harvard University. I have finished my master in December 2015 and right now I have been doing my PhD in Bioenginneering Department at the same university.
 

Abstract:

‘History is teacher of life’ as Romans expressed. It is a very significant matter of fact which contains the past, the present and the future of the societies, also has a very important place in improving the social consciousness. One of the most important duty of the mankind is to protect such a worthy history heritage. Archives that made by paper are one of the main parts of our past.

Paper can be deteriorated due to physical, chemical and biological based factors such as acidity, metal ions, lightning, heat, humidity, UV light, pollutants or biodeteriogens. Among these factors, for one, microorganisms can damage on papers irrevocably via releasing some reactive groups.

In this study focused on conservation of historical paper samples by using silver-chitosan Nano composite coating to gain antibacterial and antifungal feature. It is well known that Ag nanoparticles possess antibacterial properties. Chitosan, a polysaccharide biopolymer derived from naturally occurring chitin, displays unique polycationic, chelating and film forming properties due to the presence of active amine and hydroxyl functional groups, is a natural polymer that is both non-toxic and biodegradable. Silver-chitosan Nano composite produced at specific temperature via solvothermal method. Then produced samples are characterized via Scanning Electron Microscopy (SEM). Coating of sample papers are carried out by using three different methods that called dipping, spraying and electrospinning. Afterwards micro-organism growth tested in Süleymaniye Manuscript Library.

Biography:

Loreto M. Valenzuela has completed her PhD on Biomedical Engineering from Rutgers, The State University of New Jersey. Since 2009 she is an Assistant Professor at the Chemical and Bioprocessing Engineering Department of Pontificia Universidad Católica de Chile. Her areas of research include the use of polymers and biopolymers as biomaterials for tissue regeneration, or edible coatings for food applications, synthesis and characterization of nanorods for cell therapy, and molecular dynamics simulations.

Abstract:

Magnetic NanoRods (NR) have been used inside cells to deform cytoplasm and cellular membrane, and to generate cell death. Cell death has been studied as selective therapy against malign cells. However, the mechanism of action that leads to this kind of death remains unknown. To describe this mechanism, we analyzed cell membrane integrity after been treated with magnetic NRs that rotate at low frequency and NRs effect on cell proliferation rate. To do this, we fabricated Ni-Pt NRs by electrodeposition into porous alumina templates, being one of the first studies that analyze Pt particles of this size inside any kind of cells. We designed a low frequency Magnetic Field (MF) generation system with temperature control to allow NRs to rotate inside cells avoiding thermal stress. We incorporate NRs to fibroblast NIH/3T3 cell culture and after one day MF was applied. Membrane integrity was identified by specific dye 20 minutes after treatment. We confirmed NR incorporation by a microscopy video of a single NR rotating inside a single cell and bouncing against its membrane. Membrane integrity damage was only found in cells treated simultaneously with NRs and MF, thus cell death mechanism is necrotic-like since apoptosis needs more time to occur. Proliferation inhibition was observed on cultures with NRs, indicating that particles alter cell cycle and needs to be functionalized to be biocompatible. This will allow us to understand the effect of NRs on cell death.

Biography:

Ayomide H, Labulo has his expertise in synthesis of carbon nanomaterials such as carbon nanotubes, carbon spheres, carbon fiber and amorphous carbon. He also specializes in characterization of nanomaterials using different instruments such as raman spectroscopy, transmission electron microscope, scanning electron microscope, thermogravimetric analysis, X-ray diffraction among others. His present focus is the application of nitrogen doped carbon nanoparticles for catalytic hydrogenation

Abstract:

Novel ferrocenyl-imidazolium compounds were synthesized and used as catalyst for the synthesis of shaped carbon nanomaterials (SCNMs).  Chemical vapour deposition (CVD) technique was used with acetonitrile and aniline as both nitrogen and carbon source, respectively at 850^oC.  In this study, the effect of substituents on the ferrocenyl-imidazolium catalyst to produce shaped carbon nanomaterials such as carbon sphere (CS), amorphous carbon (AC), carbon fibre (CF) and nitrogen-doped carbon nanotubes (N-CNTs) were investigated.  Bamboo-like N-CNTs were obtained in good yield.  Characterization was done using transmission electron microscopy, scanning electron microscopy, high resolution transmission electron microscopy, raman spectroscopy and thermogravimetric studies.

Biography:

He is present working at Center for Nanoscience and Nanotechnology (C2N), CNRS, Universite Paris-Saclay,France.
 

Abstract:

The extreme light confinement provided by sub-wavelength metal-dielectric structures
pushes towards revisiting the design rules of the photo-detectors. Furthermore,
introducing absorbing layers in optical nano-resonators demands a dedicated
electromagnetic design. Developing together semiconducting heterostructures and
optical nano-antennas opens the way for performance improvements and new
functionalities, introducing very promising features such as ultra-thin absorbing layers
and device area much smaller than its optical cross-section. High responsivity, highspeed
behavior, and carved optical response are among the expected properties of this
new generation of photo-detectors.
In this talk, I present a GMR InGaAs photo-detector dedicated for FPA applications as an
illustration of this global design. I discuss the cross-linked properties of the optical and
semiconductor structures. Experimental results show at λ = 1.55 μm an EQE of 75% and
a specific detectivity of 1013 cm.√Hz.W-1.

Biography:

Pouneh Torabi received the B.S. degree in physics and the M.S. degree from the University of Tabriz, Tabriz, Iran, where her research is based on biosensors based on QDs.Moubeh Dolatyari received the B.S. degree in chemistry, the M.Sc. degree in inorganic chemistry, and the Ph.D. degree in inorganic solid-state chemistry from the University of Tabriz, Tabriz, Iran, in 2004, 2006, and 2010, respectively. From 2007 to 2008, she was a Visiting Student with the Research Group of Prof. Meyer in the University of Koeln, Cologne, Germany; from 2010 to 2012, she was a Postdoctoral Researcher with the Research Group of Prof. Rostami; and then was an Assistant Professor with the School of Engineering-Emerging Technologies, University of Tabriz. She is currently the Founder and Director of Research Labs in ASEPE Company, Tabriz, Iran.

Abstract:

Fluorescence resonance energy transfer (FRET) effects of Anti-EGFR antibody on synthesized CdS, CdSe, ZnS, ZnSe, Bi₂Se₃ and Bi₂S₃ quantum dots (QDs) is studied in this paper. The obtained results indicate significant FRET increasing for Anti-EGFR antibody attachment of CdS, CdSe, ZnS, ZnSe and Bi₂Se₃ quantum dots. Higher intensity is observed for anti-EGFR -ZnS quantum dots. For anti-EGFR -Bi₂S₃ quantum dots decreasing in florescence spectrum observed rather than Bi₂S₃ quantum dots.

Biography:

J. Jou has completed his PhD in 1986 from University of Michigan, Ann Arbor, Michigan, USA, and worked as a postdoctoral visiting scientiest at IBM-Almden Research Center, San Jose, CA, USA from 1986 to 1988, before joining National Tsing Hua University. He has published more than 140 papers in reputed journals and been granted more than 60 patents from USA, China and Taiwan.

Abstract:

Nano structures enable organic light-emitting diode (OLED) devices to be fabricated with with relatively high efficiency and brightness, opening up a new era for high quality displays and lighting. Along with the incorporation of nano-scale carrier-modulation-interlayer(s) in between emission layers containing sunlight emission complementary dyes, sunlight-style OLED can be obtained with color or color temperature mimicking that of the sun throughtout the entire daytime. We are also able to fabricate blue hazard free, low color temperature candlelight-style OLED by employing candlelight complementary emitters, namely orange-red, yellow, green, and sky-blue. The resultant candlelight OLED, that exhibits a 1,900K color temperature exactly like that of candles or oil lamps, is friendly to human eyes, physiologies, ecosystems, artifacts, and night-skies. Specifically, it is at least 10 times safer from retina protection perspective or 5 times better for melatonin to naturally occur after dusk, as comparing with the blue light-enriched white OLED, LED and CFL counterparts. We will hence present the device structure, physics and engineering behind the serendipity of the first sunlight-style OLED, how the nano-interlayer modulates the injection of carriers and their recombination, and why and how tremendous efforts have then after been moved to the development of  a 'good light' that is blue hazard free, high in light-quality and   energy-saving. The presentation will also cover global attention and development progress of the candlelight OLED.

Biography:

Xochitl Dominguez Benetton completed her PhD at the Mexican Petroleum Institute. She started her early career as a Research Professor at the University of Yucatan, in Mexico, followed by Postdoctoral Research at the National Polytechnic Institute of Toulouse, in France. Currently, she is a Senior Scientist at the Flemish Institute for Technological Research where she has conducted research on Electrochemical Systems, leading to more than 40 papers in reputed journals, as well as 5 patents. She invented the process of gas-diffusion electrocrystallization, and is currently developing a wide-ranging library of functional nanomaterials.

Abstract:

Gas-diffusion electrocrystallization (GDEx) is a new electrochemical process that conveys the synthesis of crystalline nanomaterials with well controlled and narrowly distributed properties that relate to specific functionalities. GDEx is a one-pot rapid process involving a porous cathode, an aqueous electrolyte containing metal or metalloid ions, and an oxidant gas, in which colloidal dispersions of nanomaterials or solid nanoparticles are synthesized. The general principles and mechanism through which GDEx operates will be introduced. Cerium oxide nanoparticles with controlled crystallite sizes and compositions, which result in tunable oxygen sorption capacities and kinetics, have been synthesized using GDEx. These can be tailored for pro-oxidant or anti-oxidant applications of interest for electronic packaging, oxidative stress alleviation, or cancer therapy. GDEx has also been used to produce iron oxide nanoparticles in which the ratio of heamatite (Fe₂O₃) and magnetite (Fe₃O₄) can be tweaked, providing the possibility to regulate their magnetic susceptibility. These materials are studied for molecular diagnostics. Solid nanoparticles of herbertsmithite, have been obtained. These Cu/Zn-based nanoparticles may have applications in data storage, high-temperature superconductors and for so-called “quantum-entangled” batteries. Finally, when using manganese, compositions with birnessite and hausmannite — which may intercalate water and alkali metals — have been synthesized, providing promising materials for batteries electrodes or catalysts. GDEx is revealed as a new route to synthesize a wide range of nanoparticles, flexibly and with versatile control of composition, morphology, and physicochemical parameters, which in turn tailor specific functionalities.

Biography:

Kiminori Sato has completed his PhD at Department of Applied Physics, The University of Tokyo and then Postdoctoral Studies at Institut für Theoretische und Angewandte Physik, Universität Stuttgart, Department of Physics, Washington State University, and National Institute of Advanced Industrial Science and Technology (AIST). He is now an Associate Professor of Department of Environmental Sciences, Tokyo Gakugei Univeristy.

Abstract:

Two-dimensional (2D) nanomaterials, as e.g., inorganic layered mineral, graphene, and metallic nanosheet, have been attracting increasing interest in the field of energy- and environment-related advanced materials owing to their unique properties on catalysis, adsorption, and electronic transport. It is known that the inorganic layered nanoparticles spontaneously organize into well-defined local structures through the mutual interactions of 2D nanosheets in the presence of water molecules. This spontaneous ordering of 2D nanosheets induced by water molecules, so-called self-assembly of 2D nanosheets, is found to produce the local molecular structures that is responsible for environmental functionalities Here, local molecular and electronic structures created by 2D nanosheets are explored for the purpose of enviromental application, as e.g., an improvement of Cs specific adsorption, enhancement of CO₂ adsorption, appearance of proton conductivity, and so on. The open spaces formed by 2D nanosheets with the sizes ranging from Ångstrom to nanometer are highlighted on the basis of the results of element-specific positron annihilation spectroscopy togther with molecular dynamic (MD) simulation.

Biography:

Darja Lisjak completed her PhD in 1999 at Faculty of Chemistry and Chemical Technology of University of Ljubljana. She was at Jožef Stefan Institute for most of her research time, a Visiting Researcher at University of Pennsylvania and University of Trieste, and a Senior Researcher at Center of Excellence COBIK. She is now a Senior Researcher at Department for Materials Synthesis at Jožef Stefan Institute and an Associated Professor at Jožef Stefan International Postgraduate School. She published more than 85 scientific papers and was awarded, together with Prof. Alenka Mertelj, a Zois recognition for the development of ferromagnetic suspensions.

Abstract:

Functionality of materials can be enriched by the anisotropy. Crystalline and/or shape anisotropy of materials results in orientationally dependent physical properties. For example, a class of materials, named hexaferrites, shows uniaxial magnetic anisotropy due to their anisotropic crystal structure of magnetoplumbite type. Hexaferrites crystallize in the shape of thin hexagonal platelets with a magnetic easy in the direction of the c-crystal axis, i.e., perpendicular to the basal crystal plane. Consequently, a single hexaferrite platelet forms a nanomagnet, with a direction dependent response to an applied magnetic field. In order to exploit the platelets' specific magnetic properties they should be synthesized in wet and used in the form of stable suspensions. Subsequently, plate-like nanomagnets can be: (i) embedded in different matrices to form composites, (ii) assembled from the suspensions into higher structures, films or bulk materials, or (iii) hybridized with functional organic moieties; all resulting in new advanced materials. In this contribution we present our original approach for the synthesis of hexaferrite plate-like nanomagnets, including the possibilities for tuning different interparticle forces that allowed for the development of self-biased thick films, new magneto-optic composites and ferromagnetic suspensions. A specific role of the magnetocrystalline and shape anisotropy of these nanomagnets for the realization of the new advanced material will be elucidated and their potential applications will be presented.

Biography:

Fernando A Castro is the Knowledge Leader for the Engineering, Materials and Electrical Science Department at the UK’s National Physical Laboratory. He also holds several international roles, such as Chair of TWA36 Organic Electronics of VAMAS, UK Expert within IEC TC119 - Printed Electronics, Associate Editor of the journal Science and Technology of Advanced Materials, Member of the Steering Committee of the European Energy Research Alliance – JP Photovoltaics. He has chaired large international conferences on Nanomaterials, Metrology and Photovoltaics, has delivered over 30 keynote/invited talks and has publised over 50 papers in high-quality peer-review journals.

Abstract:

Numerous new technologies rely on understanding the key role of nanoscale properties in defining the performance of electronic and optoelectronic devices. This has required the development of new measurement techniques, that can probe different device properties at increasing spatial resolution. However, despite significant progress, existing nanoscale characterisation techniques normally can only measure either electrical or spectroscopic properties, but not both simultaneously. This makes correlation of structure and property very challenging. Additionally, high-resolution information is rarely obtained simultaneously in all three dimensions. For instance, scanning probe measurements allow high lateral resolution but are typically surface techniques, with poor information about the subsurface. In this presentation, we demonstrate a novel method that allows non-destructive, simultaneous measurements of topographical, electrical and optical microscopy at the nanoscale (<20 nm resolution) by combining tip-enhanced optical spectroscopy (photoluminescence and Raman) with photocurrent AFM. We demonstrate that this approach offers subsurface sensitivity that can be exploited to provide molecular information with nanoscale resolution in all three spatial dimensions. We apply this method to organic solar cells and show that we are able to correlate local nanoscale composition to photocurrent generation, including the direct identification of impurities within nanoscopic domains of operating solar cells. The multi-parameter measurement approach demonstrated here, allows to directly identify the impact of film nanostructure on optoelectronic function and avoids the challenge associated with post processing image registration, sample contamination or degradation when measurements are performed separately. We expect it will play a significant role in guiding the design of nanomaterial-based optoelectronic devices.

Biography:

P. M. Dinh received her Ph.D. in 2002 in high energy nuclear physics (Institute for Theoretical Physics in Saclay, France), and has been recruited in 2003 at the Laboratory for Theoretical Physics of Toulouse. She now works on the theory of multi-electronic systems (clusters, molecules) excited by intense electromagnetic fields (lasers, charged projectiles), within time-dependent density functional theory (TDDFT) and beyond. She is a developer of the TDDFT code "TELEMAN". She has published 59 referred articles including 3 reviews and 3 book chapters, and wrote 3 books. She is a Junior member of the Institut Universitaire de France since 2012.

Abstract:

The quantum description of dissipative mechanisms in finite quantum systems is a long standing question in physics. It was originally addressed in nuclear physics, in particular a few decades ago, with the development of classical and semiclassical approaches but without no convincing fully quantum one. Therefore, many dynamical scenarios (where quantum effects still play a role in spite of dissipative trends) cannot be treated. Meanwhile, a strong experimental motivation, now in the case of nanostructures and molecules irradiated by intense lasers, has shown up. This motivated an increasing number of theoretical investigations, mostly on the basis of the well developed Time Dependent Density Functional Theory (TDDFT) provides a robust effective mean field description of many low energy dynamical scenarios. Still, these TDDFT approaches fail to account for dissipative effects leading to the (observed) electronic pattern. There is thus a crucial need for a formal and practical route to account for dissipative/thermalization features on top of quantum mean field. We propose here a formalism allowing to describe the collisional correlations responsible for thermalization effects in finite quantum electronic systems. The approach is built as a stochastic extension of TDDFT. Dynamical correlations are treated in time-dependent perturbation theory and stochastic loss of coherence is assumed at some time intervals. This theory was formulated long ago for density matrices but never applied in practical cases because of its computational involvement. With a recent reformulation of the theory, applications are now conceivable and first tests have been successfully led in a simplifed 1D model.

Biography:

Dr. Yoshitaka Fujimoto received his Ph.D. degree in Engineering from Osaka University, Japan. After receiving his Ph. D., he worked at the University of Tokyo and the University of Tsukuba. He joined Department of Physics, Tokyo Institute of Technology as an Assistant Professor. He has published more than 50 technical papers in peer-reviewed journals, reviews, book, book chapters, etc. and has served as referee of many international journals, organizer and committee in conferences.

Abstract:

Since experimental realization of a graphene sheet, two-dimensional atomic-layer sheets have received much attention from the viewpoint of nanoscience and nanotechnology. Among them, hexagonal boron nitride (h-BN) atomic-layer sheets are also expected to an important material since they possess several superior properties similar to a graphene. In the aspect of the electronic structures, both two materials exhibit considerably different features; graphene is a zero-gap material, whereas h-BN monolayer is a wide-gap material. One of the effective ways to tune electronic properties of nanomaterials is to apply strains to them. For example, the band gaps and the impurity states of h-BN monolayers are tunable by applying strains [1,2].
In this talk, I will report strain effects on the stabilities and the electronic properties of h-BN atomic layers using first-principles density-functional calculations [3,4]. I demonstrate the possible methods to tune the band gaps and the ionization energies of the impurity induced states in h-BN atomic layers. We also discuss the relationship among applied strains, band gaps and the impurity-related states of h-BN atomistic layers.

Biography:

Dominique Ausserré has completed his PhD in Collège de France, Paris, has been visiting scientist in IBM, San Jose, the co-strated a soft matter lab  in Institut Curie, Paris, and then moved to Le Mans University in 1991.  He is Research Director in CNRS, France, and worked in the fields of  optics, polymer and statistical physics, material science, capillarity and surface physical chemistry, now moving towards biology and healthcare oriented technological developments. He invented self-assembled nano-composite materials made of nanoparticles and diblock copolymeris, self-assembled polar lamellar materials named Ferrochemicals, and the SEEC and BALM optical techniques. He was co-founder of two startups : Nanoraptor and Watch Live.      

Abstract:

BALM is a new wide field optical microscopy which is remarkably suited for nano enginnering. Most of the time, nano-objects have to be fixed on surfaces in order to be localized, handled, or used in combination with some environmental control. BALM is a surface imaging technique wich combines extreme (say SPR-like) sensitivity with full optical resolution. Moreover, its implementation  is confined in the half-space located below the sample, so that the upper half-space remains free for implementing environmental tools such as a fluidic cell, spectroscopic tools such as Raman analysis,  local measuring tools such as electrical and SPM probes or local fields of any type.  At last, it is a real time technique, hence offering large possibilities for kinetic studies.

Thanks to a close collaboration with Vincent Dreycke, Stephane Campidelli and Renaud Cornut in the LICSEN group of CEA Saclay, the power of the technique in the study of 2D materials was recently demontrated ¹  . 

The aim of this talk is to forecast the next coming BALM applications, supported by preliminary results obtained  with various kinds of nanoparticles, sensor chips and solid liquid interfaces. The first principles of the technique will also be exposed.

Biography:

Andriy Kovalenko is Senior Research Officer at the National Institute for Nanotechnology since 2003, and Adjunct Professor in the Department of Mechanical Engineering at the University of Alberta, Edmonton, Canada. He earned his PhD degree (1993) in Theoretical and Mathematical Physics from Lviv State University, Bogolyubov’s Institute. He has been developing methodology and software implementation of statistical-mechanical, molecular theory of solvation, coupling it with electronic structure theories, molecular simulations, and docking protocols in a platform of predictive multiscale theory & modeling of chemical, supramolecular, and biomolecular systems constituting new advances towards a general framework of multiscale methods.

Abstract:

In recent two decades, molecular theory of solvation for nanostructures in both aqueous and non-aqueous solutions, a.k.a. three-dimensional reference interaction site model (3D-RISM) with the Kovalenko-Hirata (KH) closure relation, was systematically developed and applied to a variety of compounds, supramolecules, and biomolecules in a number of solvents, solvent mixtures, electrolyte and non-electrolyte solutions. From the first principles of statistical mechanics, 3D-RISM-KH theory predicts the solvation structure and thermodynamics of nanochemical and biomolecular systems, including their analytical long-range asymptotics. It yields improved accuracy, efficiency, and applicability by coupling models and methods at different space and time scales to provide fundamental understanding and prediction for nanomaterials and biomolecules. The method has been coupled with quantum chemistry, molecular dynamics, and dissipative particle dynamics. Examples include helical rosette nanotubes with tunable stability and hierarchy, water promoted inversion of supramolecular chirality, formation and stability of self-assembling supramolecular structures of organic rosette nanotubes with ordered shells of inner and outer water, and highly accurate & efficient dissipative particle dynamics of polymer chains with coarse-grained effective pair potential obtained from DRISM-KH theory. Recent applications of 3D-RISM-KH consist in multiscale coupling of quantum chemistry, molecular solvation theory, multi-time step molecular dynamics, and dissipative particle dynamics. Calculations show the dependence of the polymerization degree on organic solvents properties and temperature/pressure change. Aggregation of kaolinite platelets due to face-to-face, edge-to-face, and edge-to-edge interactions and temperature/pressure strongly affect bioadsorption on clays and flocculation of clay nanoparticles in aqueous and non-aqueous solutions with polymers. Multi-Time-Step Molecular Dynamics coupled with 3D-RISM-KH molecular solvation theory and Generalized Solvation Force Extrapolation (MTS-MD/3D-RISM-KH/GSFE) provides quasidynamics description of biomolecules. Validation included folding of miniprotein in solution from fully extended to equilibrated state in 60 ns, which provides acceleration by two orders of magnitude time scale as compared to 4-9 µs protein folding in experiment.

Biography:

Hyung Ho Park is a Professor in the Materials Science & Engineering Department of Yonsei University in Korea since 1995. His research focuses on the preparation, characterization, and application of various functional thin films including nano-particle preparation, nano-hybridization, and nanostructure formation. Nano-hybrid thin films are prepared by the incorporation of nano-particles or in situ one-pot synthesis. Nanostructure formation involves nano-particle distribution in TCO and organic conductors and the control of nano-pore size and distribution in mesoporous thin films. He has published more than 380 SCI(E) papers in reputed journals and has been serving as an Editorial Board Member of more than 5 journals.

Abstract:

Mesoporous oxides have a structure containing nano-sized pores of 2~50 nm and are prepared by sol-gel procedure using evaporation induced self assembly. The pore size, pore distribution (regular/irregular, open/close), and pore shape can be controlled according to the synthetic process, especially with surfactant molar ratio. The existence of pores in the material grants distinctive properties such as decreased thermal conductivity from increasing phonon scattering. Therefore mesoporous oxides can be used in many applications such as thermal insulators, thermoelectrics, gas sensors, and so on. The efficiency of a thermoelectric is determined by its dimensionless figure of merit, Z = S²σ/κ where S, σ, and κ are the Seebeck coefficient, electrical conductivity, and thermal conductivity, respectively. According to this equation, good thermoelectric material should possess large power factor (PF = S²σ) and low thermal conductivity. When introducing the pore structure, thermal conductivity can be greatly decreased but also with electrical conductivity due to electron scattering by pore structure. So, in the case of mesoporous structure adoption to thermoelectric materials, a minimum reduction in electrical conductivity while maximizing thermal isolation effect is a key issue for an enhancement in the thermoelectric property. In this presentation, various experimental approaches including a control of pore structure and introductions of dopants and nano-materials to enhance the thermoelectric property are discussed. Through the approaches, we tried to control the thermal conductivity and electrical conductivity of mesoporous oxides individually to maximize the thermoelectric property.

Biography:

Alexander Krivcov is doing his PhD at the University of Applied Sciences Kaiserslautern with the topic “Characterisation of superparamagnetic nanoparticles for biomedical applications with Magnetic Force Microscopy (MFM)”.

Abstract:

Superparamagnetic nanoparticles (SPNs) are of increasing  interest in biomedicine. The wide range of applications, from diagnostic (Magnetic Resonance Imaging, MRI) to cancer-cells treatment (hyperthermia), promises an intensive use possibility. However, detection and characterization of SPNs at single particle level especially in biological samples remains a challenge. Therefore, techniques which can provide spatial distribution and magnetic properties of single magnetic nanoparticles are highly desirable.

Magnetic Force Microscopy (MFM) can be used to detect and spatially localize single SPNs. However, arising magnetic signal from nanoparticles could be disturbed and covered by other existing forces. One of the strongest disturbing forces is the electro-static behaviour of the probes. Due to the conductivity of the MFM measuring tip, both, magnetic and electro-static, forces are detected simultaneously.

In this work different approaches to minimize the electro-static interaction between probe and tip are discussed. We showed the possibility to reduce the electro-static force by choosing substrates with higher conductivity. Furthermore the electro-static behaviour can be reduced using Electrostatic Force Microscopy (EFM) and Kelvin Probe Force Microscopy (KPFM) combined with MFM.

Those approaches are investigated to select the magnetic force and therefore allow MFM to serve as an excellent detecting technique which makes it possible to localize single magnetic nanoparticles on substrates, embedded in polymers and injected in biomaterial.

Biography:

She is Faculty member of National Institute of Genetic Engineering and Biotechnology since 2002 and also Research assistant in an Institute of Biochemistry and Biophysics (IBB), Tehran University since 2005-2009.

Abstract:

α-Synuclein (α-Syn) is  a protein presence in the brains of a range of neurodegenerative disorders’ patients as plaque-like compact structures in the form of amyloid fibrils.  There is a strong relationship between α-Syn amyloid fibrillation and the pathology of the neurodegenerative disorders such as Parkinson’s disease. There is a serious effort to apply the compounds, known as small molecules, with inhibitory effects on the different steps of α-SN fibrillation and also its related neurotoxicity. However, the small molecules can possess some problems like high hydrophobicity/ low solubility in physiological fluids, instability, and difficulty in passing across blood brain barrier (BBB). In this respect, employing of nanocarriers has been pointed because of a lot of advantages i.e. biocompatibility, easy surface modification, low immunogenicity, protecting cargo against enzymatic degradation. In this regard we used three different nanocarriers including serum albumin nanoparticles (SA- NPs)([1], mesoporous silica nanoparticles (MS-NPs) [2] and neutral charged nanoliposomes(NC-NLPs). We found that each kind of nanocarrier possess specific characters when applying for loading drugs or treating α-Syn or neuronal cells. SA- NPs with a moderate drug loading efficiency (DLE) for polyphenols, showed some inducing effect on α-Syn fibrillation when treating with bare SA- NPs. Although MS-NPs with similar DLE did not show inducing effect on α-Syn fibrillation, they had a small neurotoxicity effect. On the other hand,  NC-NLPs had high DLE for polyphenols and also they did not indicate any considerable induction on the α-Syn fibrillation or any neurotoxicity effects. It seems that NC-NLPs have more potential for using regarding synucleinopathies treating than the two other NPs.

Biography:

Xiaoling Lu is pursuing her PhD study at University of Applied Sciences Kaiserslautern, Germany. Her academic focus is about reduced graphene-oxide based opto-electronic biosensor platform for detecting prostate cancer biomarkers.

Abstract:

Chemically exfoliated graphene-oxide (GO) is being exploited due to its similarity to graphene and tested out as an alternative to overcome the dilemma that graphene is facing towards wafer-scale and robust device preparation. In this work, we prepared GO thin-films in the manner of wafer scale by the spin-coat technique on the top of interdigitated electrodes (IDEs) with glass as substrates. The isolated GO thin-films are transformed into conductive rGO thin-films by thermal reduction. The residual -COOH groups on the surface of rGO thin film provide diverse possibilities of chemical functionalization to covalently immobilize the receptor molecules. An in-line impedimetric spectroscopy based rGO thin-films as transducer layers are tested out for label-free detection of Prostate Cancer Specific Antigen (PSA). This established biosensor exhibits ultra-sensitivity and announced sensing range because of the combination effect of tunable fermi level and fast charge/discharge behaviour of nanocapcitors. The pronounced PSA detection scale ranges from 33 fM to 330 nM at frequency 1000 Hz.