Esra Cihan
Izmir Institute of Technology, Turkey
Title: Polymeric micelle embedded chitosan nano particles as hydrophobic drug carrier
Biography
Biography: Esra Cihan
Abstract
When formulated in a nano-particulate form, chitosan (CS) has proved to be a very eff ective agent for drug delivery owing to its extremely attractive properties such as its pH sensitive character and its solubility in aqueous medium. Therefore, the synthesis of micelle embedded chitosan nano particles that are suitable for oil soluble drugs was the purpose of this study. However, even production of nano-sized chitosan particles with well-defined morphology and stability is diffi cult by using the classical gelation route. Therefore, a new production method that combines ionic gelation and three phase emulsion (o/w/o) techniques in an interesting way was used and micelle embedded chitosan nano particles were able to manufacture successfully. These nano-particles were then characterized using TEM, FTIR and DLS-LDV.